New classes of carbazoles as potential multi-functional anti-Alzheimer's agents.
Choubdar N, Golshani M, Jalili-Baleh L, Nadri H, Küçükkilinç TT, Ayazgök B, Moradi A, Moghadam FH, Abdolahi Z, Ameri A, Salehian F, Foroumadi A, Khoobi M.
Choubdar N, et al.
Bioorg Chem. 2019 Oct;91:103164. doi: 10.1016/j.bioorg.2019.103164. Epub 2019 Jul 29.
Bioorg Chem. 2019.
PMID: 31398601
Moreover, compound 3s could significantly protect PC12 cells against H(2)O(2)-induced toxicity. The results suggested that the compounds 3s could be considered as a promising multi-functional agent for further drug discovery development against Alzheimer's disease....
Moreover, compound 3s could significantly protect PC12 cells against H(2)O(2)-induced toxicity. The results suggested that the compou …